Biochip
AssigneeMWG-Biotech AG
InventorsHorst Donner, Bernd Drescher, Andrea Huber, Jaqueline Weber
Life of this patent
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Abstract
1. Biochip for the most comprehensive possible detection of the genome of Escherichia Coli K 12. 2.1 The intention is to provide devices to facilitate the most comprehensive possible analysis of the genome of Escherichia Coli K 12. 2.2 A biochip is provided with a multiplicity of probe spots, with a probe applied in each probe spot, each probe having a multiplicity of probe molecules, and all probe molecules of a probe having an identical probe sequence, wherein the probe sequences are nucleotide sequences, and one or more of the probes has probe sequences with a length of at least 20 bases, identical or complementary to a section of an Open Reading Frame of Escherichia Coli K 12.
Claims19
Biochip with a multiplicity of probe spots wherein a probe is applied in each probe spot, each probe has a multiplicity of probe molecules, wherein
- the probe sequences are nucleotide sequences,
- the probe sequences have a base length of 30-80 bases,
- the nucleotide sequences are made of ex-situ synthesised oligonucleotide sequences, and
- at least one of the probes has a probe sequence which is identical or complementary to a section of an Open Reading Frame of Escherichia Coli K 12.
Process for determining oligonucleotide sequences for a biochip, wherein sequences of a length of n bases from within an Open Reading Frame (ORF) are chosen and wherein it is tested whether the sequences exist only once within the corresponding ORF.
Dependencies are inferred from the claim text.