Human cDNAs and proteins and uses thereof
AssigneeGenset S.A.
InventorsStephane Bejanin, Hiroaki Tanaka
Life of this patent
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Abstract
The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.
Claims13
An isolated polynucleotide, comprising a nucleic acid sequence selected from the group consisting of:
- a) a polynucleotide of an odd SEQ ID NO. 1-15, 21-27, 31-51, or of a human cDNA of a deposited clone, encoding at least any single integer from 6 to 776 amino acids of any one even SEQ ID NO. 2-16, 22-28, 32-52,
- b) a polynucleotide of an odd SEQ ID NO. 1-15, 21-27, 31-51, or of a human cDNA of a deposited clone, encoding the signal peptide sequence of any one even SEQ ID NO. 2-16, 22-28, 32-52,
- c) a polynucleotide of an odd SEQ ID NO. 1-15, 21-27, 31-51, or of a human cDNA of a deposited clone, encoding a mature polypeptide sequence of any one even SEQ ID NO. 2-16, 22-28, 32-52,
- d) a polynucleotide of an odd SEQ ID NO. 1-15, 21-27, 31-51, or of a human cDNA of a deposited clone, encoding a full length polypeptide sequence of any one even SEQ ID NO. 2-16, 22-28, 32-52,
- e) a polynucleotide of an odd SEQ ID NO. 1-15, 21-27, 31-51, or of a human cDNA of a deposited clone, encoding a polypeptide sequence of a biologically active fragment of any one even SEQ ID NO. 2-16, 22-28, 32-52,
- f) a polynucleotide encoding a polypeptide sequence of at least any single integer from 6 to 776 amino acids of any one even SEQ ID NO. 2-16, 22-28, 32-52 or of a polypeptide encoded by a human cDNA of a deposited clone,
- g) a polynucleotide encoding a polypeptide sequence of a signal peptide of any one even SEQ ID NO. 2-16, 22-28, 32-52 or of a signal peptide encoded by a human cDNA of a deposited clone,
- h) a polynucleotide encoding a polypeptide sequence of a mature polypeptide of any one even SEQ ID NO. 2-16, 22-28, 32-52 or of a mature polypeptide encoded by a human cDNA of a deposited clone,
- i) a polynucleotide encoding a polypeptide sequence of a full length polypeptide of any one even SEQ ID NO. 2-16, 22-28, 32-52 or of a mature polypeptide encoded by a human cDNA of a deposited clone,
- j) a polynucleotide encoding a polypeptide sequence of a biologically polypeptide of any one even SEQ ID NO. 2-16, 22-28, 32-52, or of a biologically polypeptide encoded by a human cDNA of a deposited clone,
- k) a polynucleotide of any one of a) through j) further comprising an expression vector,
- l) a host cell recombinant for a polynucleotide of a) through k) above,
- m) a non-human transgenic animal comprising the host cell of k),
- n) a polynucleotide of a) through j) further comprising a physiologically acceptable carrier.
A polypeptide comprising an amino acid sequence selected from the group consisting of:
- a) any single integer from 6 to 776 amino acids of any one even SEQ ID NO. 2-16, 22-28, 32-52 or of a polypeptide encoded by a human cDNA of a deposited clone;
- b) a signal peptide sequence of any one even SEQ ID NO. 2-16, 22-28, 32-52 or encoded by a human cDNA of a deposited clone;
- c) a mature polypeptide sequence of any one even SEQ ID NO. 2-16, 22-28, 32-52 or encoded by a human cDNA of a deposited clone;
- d) a full length polypeptide sequence of any one even SEQ ID NO. 2-16, 22-28, 32-52 or encoded by a human cDNA of a deposited clone;
- e) a polypeptide of a) through d) further comprising a physiologically acceptable carrier.
Dependencies are inferred from the claim text.