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US 2003/0118981 A1Published application
Process for reducing mineralization of tissue used in transplantation
AssigneeMedtronic, Inc.
InventorMark W. Torrianni
Life of this patent
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Abstract
A method of making a tissue-derived implantable medical device that includes contacting the tissue with a composition comprising at least one oxidizing agent prior to implantation of the medical device.
Claims30
A method of making a tissue-derived implantable medical device, the method comprising contacting the tissue with a composition comprising at least one oxidizing agent prior to implantation of the medical device.
A method for reducing mineralization of a tissue-derived implantable medical device, the method comprising:
- contacting the tissue with a composition comprising at least one oxidizing agent;
- rinsing the tissue to remove at least a portion of the oxidizing agent;
- and
- contacting the tissue with a detergent composition comprising at least one reducing agent prior to implantation of the medical device.
1 more element
A method for reducing mineralization of a tissue-derived implantable medical device, the method comprising:
- contacting the tissue with a non-phosphate buffered organic saline solution;
- contacting the tissue with a composition comprising at least one oxidizing agent;
- rinsing the tissue to remove at least a portion of the oxidizing agent;
- contacting the tissue with a first detergent composition comprising at least one ionic detergent and at least one reducing agent;
- rinsing the tissue to remove at least a portion of the first detergent composition;
- and
- contacting the tissue with a second detergent composition comprising at least one nonionic detergent, and at least one reducing agent prior to implantation of the medical device.
4 more elements
Dependencies are inferred from the claim text.