Carvedilol-galenics
AssigneeRoche Diagnostics GmbH
InventorsRolf-Dieter Gabel, Walter Preis, Alexander Wirl
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Abstract
The invention relates to a process for the preparation of fast-dissolving pharmaceutical preparations from difficultly soluble active substances, wherein an aqueous suspension is made from active substance and one or more water-soluble adjuvants and then the resulting aqueous suspension is processed, with removal of the water, by methods conventional per se, to form solid pharmaceutical preparations. The invention also relates to fast-dissolving pharmaceutical preparations of active substances having a dissolution rate of at least 70% after 30 minutes, prepared in accordance with the process of the invention.
Claims18
A process for the preparation of fast-dissolving pharmaceutical preparations from difficultly soluble active substances with a dissolution rate of at least 70% after 30 minutes, wherein an aqueous suspension is made from the active substance and one or more water-soluble adjuvants, and then the resulting aqueous suspension is processed, with removal of the water, by methods know per se, to form solid pharmaceutical preparations.
A process according to any one of claims 1 to 8, wherein the water-soluble adjuvants used are binders, fillers, disintegrating agents and/or surfactants which are conventional per se.
The invention as described above.
Dependencies are inferred from the claim text.