MB-1 analogs and uses thereof
AssigneeAgroterra Biotech Inc.
InventorsMarc Beauregard, Mylene-Claude Gagnon, Alain Doucet, Martin Williams
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Abstract
The present invention relates to protein engineering for production of analogs of MB-1. MB-1 analogs are more stable to different biochemical conditions than the native protein, and allow for improving the supplying of essential amino acids to human and animals. De novo synthesis of MB-1 analogs is principally targeted to enhance availability of essential amino acids required for farm animal production or human health.
Claims17
A method for improving supplying of at least one essential amino acid to a human or an animal, comprising administering to said human or animal at least one polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:
- 1, SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4, and SEQ ID NO:
- 5, or a fragment thereof or at least one nucleic acid sequence encoding said polypeptide.
A composition comprising at least one polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:
- 1, SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4 and SEQ ID NO:
- 5, or a functional fragment thereof, for endowing a human or an animal with at least one essential amino acid by oral administration.
A polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NO:
- 1, SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4, and SEQ ID NO:
- 5 or a functional fragment thereof.
Dependencies are inferred from the claim text.