Oral administration of lactobacillus for the maintenance of health in women during pregnancy and at other life stages, to reduce the risk of urogenital diseases
OwnerGregor Reid, Andrew W. Bruceinventors
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Abstract
The present invention provides methods and compositions for the oral administration of Lactobacillus and/or other probiotic organisms, such as Bifidobacterium, for establishment and maintenance of a healthy urogenital flora. The invention also provides methods and compositions to reduce the risk of disease, including onset of preterm labor due to vaginal and cervical infection. The invention also provides ex vivo methods of restoring healthy gastrointestinal and vaginal flora.
Claims24
A method of reducing the risk of preterm labor comprising orally administering to a mammalian subject a therapeutically effective amount of at least one probiotic organism and a pharmaceutically acceptable carrier.
An ex vivo method of establishing a healthy gastrointestinal and urogenital flora in a females comprising orally administering to a mammalian subject at least one probiotic organism isolated from said female and a pharmaceutically acceptable carrier.
An ex vivo method of restoring healthy gastrointestinal and urogenital flora in females in need thereof comprising orally administering to a mammalian subject at least one probiotic organism isolated from the individual and a pharmaceutically acceptable carrier.
A method of maintaining a healthy gastrointestinal tract in females comprising orally administering to a mammalian subject a therapeutically effective amount of at least one probiotic organism and a pharmaceutically acceptable carrier.
A pharmaceutical composition comprising at least one probiotic organism and a pharmaceutically acceptable carrier.
A method for reducing the risk of bacterial vaginosis and bacterial vaginosis pathogens comprising orally administering to a mammalian subject to a mammalian subject a therapeutically effective amount of at least one probiotic organism and a pharmaceutically acceptable carrier.
A method of stimulating host responses to pathogens comprising contacting a medical device with a therapeutically effective amount of at least one probiotic organism and a pharmaceutically acceptable carrier prior to introduction into a patient in need of such device. a therapeutically effective amount of at least one probiotic organism and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.