Novel dequalinium analogs

Abstract

A composition for protecting human skin from harmful effects of the sun, the composition comprising a topically effective amount of: (a) a first chemical compound that absorbs ultraviolet light sufficiently to reduce significantly the damage to human skin from harmful effects of ultraviolet light; and (b) a second chemical compound having the formula: (Q-L-Q)w+2Xy−z or (Q-T)u+X−v wherein: Q represents 4-E-2-R3-1-quinolinium; E represents NR1R2, COO R1, OR1, I, Br, Cl, F, or NO3 N represents a nitrogen atom; R1 and R2 independently represent hydrogen or lower alkyl; R3 represents E, hydrogen or lower alkyl; L represents a chain comprising n atoms, the atoms in the chain being t carbon atoms and 0 to approximately 0.5 t heteroatoms; the minimum value of n is 12; the maximum value of n is 22; T represents hydrogen or a chain comprising m atoms, the atoms in the chain being t carbon atoms and 0 to approximately 0.5 t heteroatoms; the minimum value of m is 6; the maximum value of m is 22; X represents an anion; w represents 1 or 3, y and z represent 1 or 2, with the proviso that 2w=yz; and u and v represent 1, 2, or 3 with the proviso that u=v.

Dependencies are inferred from the claim text.