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US 2003/0114704 A1Published application
Method of producing 3-aminoalkanoic acid esters
AssigneeLonza Ltd.
InventorRudolf Fuchs
Life of this patent
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Abstract
The invention relates to a method of producing 3-aminoalkanoic acid esters of the general formula (I), wherein R represents C1-6 alkyl, and R1 represents hydrogen, C1-6 alkyl or phenyl, or the salts thereof, by catalytically hydrating the corresponding 3-amino-2-alkenoic acid esters in the presence of a strong acid.
Claims10
Process for the preparation of 3-aminoalkanoic acid esters of the general formula
- 4
- in which R is C1-6-alkyl and R1 is hydrogen, C1-6-alkyl or phenyl, or their salts, by catalytic hydrogenation of the corresponding 3-amino-2-alkenoic acid esters of the general formula
- 5
- in which R and R1 have the abovementioned meanings, characterized in that the hydrogenation is carried out in the presence of a strong acid and the salt of the 3-aminoalkanoic acid ester (I) and the strong acid formed is optionally converted into the free 3-aminoalkanoic acid ester (I) or into another salt in a manner known per se.
1 more element
Methyl (RS)-3-ammoniobutyrate methanesulfonate.
Dependencies are inferred from the claim text.