Human cystatin F
AssigneeHuman Genome Sciences, Inc.
InventorsHaodong Li, Guo-Liang Yu, Reiner L. Gentz, Jian Ni
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Abstract
The invention relates to Cystatin F polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.
Claims24
An isolated polynucleotide comprising a polynucleotide having at least a 70% identity to a member selected from the group consisting of:
- (a) a polynucleotide encoding a polypeptide comprising an amino acid sequence as set forth in SEQ ID NO:2;
- (b) a polynucleotide encoding a polypeptide comprising amino acid 19 to amino acid 145 as set forth in SEQ ID NO:2;
- (c) a polynucleotide which is complementary to the polynucleotide of (a) or (b);
- and
- (d) a polynucleotide comprising at least 15 bases of SEQ ID NO:1.
An isolated polynucleotide comprising a polynucleotide having at least a 70% identity to a member selected from the group consisting of:
- (a) a polynucleotide which encodes a mature polypeptide having the amino acid sequence expressed by the human cDNA contained in ATCC Deposit No. 97463;
- (b) a polynucleotide which is complementary to the polynucleotide of (a);
- and
- (c) a polynucleotide comprising at least 15 bases of the polynucleotide of either (a) or (b).
A polypeptide comprising a member selected from the group consisting of:
- (a) a polypeptide having an amino acid sequence set forth in SEQ ID NO:2;
- (b) a polypeptide comprising amino acid 19 to 145 of SEQ ID NO:2;
- and
- (c) a polypeptide which is at least 70% identical to the polypeptide of either (a) or (b).
Dependencies are inferred from the claim text.