Dextrochlorpheniramine tannate
AssigneeJame Fine Chemicals, Inc.
InventorsSham N. Redkar, Raja G. Achari, Angelo R. Mellozzi, Vilas M. Chopdekar
Life of this patent
Estimating the term…
Abstract
The invention pertains to a novel composition comprising dextrochlorpheniramine tannate and to a method for preparing such tannate by reacting dextrochlorpheniramine free base at a temperature of about 60 to about 150° C. with tannic acid preferably neat or as an aqueous slurry containing about 5 to about 30 wt. % water. The dextrochlorpheniramine tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.
Claims19
A composition comprising dextrochlorpheniramine tannate.
A therapeutic antihistaminic composition comprising a pharmaceutically effective amount of an active ingredient comprising dextrochlorpheniramine tannate.
A method for suppressing the production of histamines in a human being that comprises orally administering to such human being a therapeutic amount of a composition comprising an active ingredient comprising dextrochlorpheniramine tannate.
A method for preparing dextrochlorpheniramine tannate which comprises reacting dextrochlorpheniramine free base with tannic acid at a temperature of about 60 to about 150° C. and thereafter recovering the resultant dextrochlorpheniramine tannate.
Dependencies are inferred from the claim text.