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US 2003/0114515 A1Published application
Therapeutic mixture of HMG-COA reductase inhibitors
OwnerWayne H. Kaesemeyerinventor
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Abstract
Therapeutic mixtures of statins alone or in combination with L-arginine are described herein.
Claims19
A composition comprised of
- a first Hmg-CoA reductase inhibitor;
- and
- a second Hmg-CoA reductase inhibitor, said first and second Hmg-CoA reductase being different.
A therapeutic composition comprising:
- a hydrophilic HMG-CoA reductase inhibitor, and;
- a hydrophobic HMG-CoA reductase inhibitor.
A method for treating cardiovascular disease in a mammal comprising:
- administering a hydrophilic HMG-CoA reductase inhibitor to a patient in need of such treatment, and;
- administering a lipophilic HMG-CoA reductase inhibitor to a patient.
The method of claim 18, wherein said hydrophilic Hmg-CoA reductase inhibitor is pravastatin.
- The method of claim 19, wherein said lipophilic Hmg-CoA reductase inhibitor is atorvastatin.
Dependencies are inferred from the claim text.