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US 2003/0114494 A1Published application
Stable galenic preparations comprising a benzimidazol and method for the production thereof
Assigneeratiopharm GmbH
InventorBenoit Schmitt
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Abstract
The invention relates to a novel benzimidazole formulation and to a process for its production. The benzimidazole formulation comprises a layer comprising the benzimidazole compound together with an acidic reacting compound.
Claims15
An oral pharmaceutical in the form of pellets comprising a benzimidazole compound of the formula I
- 3
- in which R1 is hydrogen, methoxy or difluoromethoxy, R2 is hydrogen, methyl or methoxy, R3 is methoxy, 2,2,2-trifluoroethoxy or 3-methoxypropoxy, and R4 is hydrogen, methyl or methoxy, comprising
- (a) an inert core,
- (b) thereon an active ingredient layer which comprises the benzimidazole compound of the formula I mixed with an acidic reacting compound and, where appropriate, pharmaceutically acceptable adjuvants,
- (c) at least one inert layer and
- (d) an outer layer which is applied to the inert layer and which comprises an enteric coating.
3 more elements
Dependencies are inferred from the claim text.