Benzoic acid derivatives, processes for producing the same and drugs containing the same as the active ingredient

A benzoic acid derivative of formula (I)

• 138
• , wherein
• 139
• are each independently, C3˜7 carbocyclic ring or 5˜7 membered heterocyclic ring containing nitrogen, sulfur and/or oxygen atom,
• D is C1-4 alkylene, oxygen or sulfur atom,
• G is oxygen or sulfur,
• E is a bond, oxygen, sulfur, C1-4 alkylene, C1-4 alkyloxy or C1-4 oxyalkyl,
• R1 is hydroxy, —OR9 or —NR10R11, wherein R9 is C1-6 alkyl, and
• R10 and R11 are each independently, hydrogen atom or C1-6 alkyl,
• R2 and R3 are each independently, C1-4 alkyl, C1-4 alkoxy, halogen atom, trihalomethyl, cyano or nitro,
• R4 is hydrogen or C1-6 alkyl,
• R5 is a bond, C1-6 alkylene, C1-6 alkylene substituted with C1-4 alkoxy, or C3-5 cycloalkylene,
• R6 is C5˜15 carbocyclic ring or 5-15 membered heterocyclic ring containing nitrogen, sulfur and/or oxygen,
• R7 is hydrogen, C1-8 alkyl, C5˜7 carbocyclic ring or 5-15 membered heterocyclic ring containing nitrogen, sulfur and/or oxygen,
• m and n are each independently, 0, 1, 2 or 3.
• The rings represented by R6 and R7 may be substituted with C1-4 alkyl, C1-4 alkoxy, halogen, trihalomethyl, nitro, cyano or oxo,
• with proviso that 2-[2-(benzoylamino)phenylmethyl]benzoic acid is excluded,
• or a non-toxic salt thereof.