Method for the treatment and prevention of pain and inflammation with glucosamine and a cyclooxygenase-2 selective inhibitor and compositions therefor
AssigneePharmacia Corporation
InventorsSteven P. Pulaski, Susan Kundel
Life of this patent
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Abstract
A method of treating, preventing, or inhibiting pain, inflammation or inflammation-associated disorder in a subject in need of such treatment or prevention provides for treating the subject with glucosamine and a cyclooxygenase-2 selective inhibitor or prodrug thereof, wherein the amount of glucosamine and the amount of a cyclooxygenase-2 selective inhibitor or prodrug thereof together constitute a pain or inflammation suppressing treatment or prevention effective amount of the composition. Compositions and pharmaceutical compositions that contain glucosamine and a cyclooxygenase-2 selective inhibitor are also disclosed.
Claims59
A method for the treatment, prevention, or inhibition of pain, inflammation or inflammation-associated disorder in a subject in need of such treatment, prevention, or inhibition, comprising administering glucosamine and a cyclooxygenase-2 selective inhibitor or prodrug thereof to the subject.
A method for the treatment or prevention of disorders having an inflammatory component in a subject in need of the treatment or prevention of disorders having an inflammatory component, the method comprising administering to the subject a therapeutically effective dose of glucosamine and cyclooxygenase-2 selective inhibitor or a pharmaceutically acceptable salt or prodrug thereof
A composition for the treatment, prevention, or inhibition or pain, inflammation, or inflammation-associated disorder comprising glucosamine and a cyclooxygenase-2 selective inhibitor or prodrug thereof.
A pharmaceutical composition comprising glucosamine;
- a cyclooxygenase-2 specific inhibitor or prodrug thereof;
- and a pharmaceutically-acceptable excipient.
A kit that is suitable for use in the treatment, prevention or inhibition of pain, inflammation or inflammation-associated disorder, the kit comprises a first dosage form comprising glucosamine and a second dosage form comprising a cyclooxygenase-2 selective inhibitor or prodrug thereof, in quantities which comprise a therapeutically effective amount of the compounds for the treatment, prevention, or inhibition of pain, inflammation or inflammation-associated disorder.
Dependencies are inferred from the claim text.