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US 2003/0114370 A1Published application
Nucleic acid molecules encoding endostatin protein and peptide fragments thereof
OwnerM. Judah Folkman, Michael S. O'Reillyinventors
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Abstract
Endostatin compositions capable of inhibiting endothelial cell proliferation, inhibiting angiogenesis and causing tumor regression are described. Specifically, amino acid sequences of endostatin proteins and nucleic acid sequences coding for endostatin proteins are provided.
Claims20
An isolated endostatin protein, wherein the protein has an amino acid sequence selected from the group consisting of SEQ ID NO:3 and SEQ ID NO:5.
An isolated nucleic acid molecule having a sequence encoding an endostatin protein, wherein the nucleic acid sequence is selected from the group consisting of SEQ ID NO:4 and SEQ ID NO:6.
Dependencies are inferred from the claim text.