Composition for the prevention and/or treatment of artherosclerosis

An immunological and oral tolerance-inducing composition for prevention and/or treatment of a heart attack by the oral administration thereof, comprising an active component selected from the group consisting of modified low density lipoprotein, oxidized low density lipoprotein (Ox LDL), heat shock protein 60/65 (HSP 60/65), beta2-glycoprotein-1 (β2GP-1), functional derivatives thereof and mixtures thereof, in combination with a pharmaceutically acceptable carrier for oral administration.

An immunological and oral tolerance-inducing composition for prevention and/or treatment of angioplasty-restenosis by the oral administration thereof, comprising an active component selected from the group consisting of modified low density lipoprotein, oxidized low density lipoprotein (Ox LDL), heat shock protein 60/65 (HSP 60/65), beta2-glycoprotein-1 (β2GP-1), functional derivatives thereof and mixtures thereof, in combination with a pharmaceutically acceptable carrier for oral administration.

An immunological and oral tolerance-inducing composition for prevention and/or treatment of stroke by the oral administration thereof, comprising an active component selected from the group consisting of modified low density lipoprotein, oxidized low density lipoprotein (Ox LDL), heat shock protein 60/65 (HSP 60/65), beta2-glycoprotein-1 (β2GP-1), functional derivatives thereof and mixtures thereof, in combination with a pharmaceutically acceptable carrier for oral administration.

A method for prevention and/or treatment of atherosclerosis in a subject, comprising orally administering an immunological and oral tolerance-inducing composition comprising an active component selected from the group consisting of modified low density lipoprotein, oxidized low density lipoprotein (Ox LDL), heat shock protein 60/65 (HSP 60/65), beta2-glycoprotein-1 (β2GP-1), functional derivatives thereof and mixtures thereof, in combination with a pharmaceutically acceptable carrier for oral administration.

A method for prevention and/or treatment of a heart attack in a subject, comprising orally administering an immunological and oral tolerance-inducing composition comprising an active component selected from the group consisting of modified low density lipoprotein, oxidized low density lipoprotein (Ox LDL), heat shock protein 60/65 (HSP 60/65), beta2-glycoprotein-1 (β2GP-1), functional derivatives thereof and mixtures thereof, in combination with a pharmaceutically acceptable carrier for oral administration.

A method for prevention and/or treatment of angioplasty-restenosis in a subject, comprising orally administering an immunological and oral tolerance-inducing composition comprising an active component selected from the group consisting of modified low density lipoprotein, oxidized low density lipoprotein (Ox LDL), heat shock protein 60/65 (HSP 60/65), beta2-glycoprotein-1 (β2GP-1), functional derivatives thereof and mixtures thereof, in combination with a pharmaceutically acceptable carrier for oral administration.

A method for prevention and/or treatment of stroke in a subject, comprising orally administering an immunological and oral tolerance-inducing composition comprising an active component selected from the group consisting of modified low density lipoprotein, oxidized low density lipoprotein (Ox LDL), heat shock protein 60/65 (HSP 60/65), beta2-glycoprotein-1 (β2GP-1), functional derivatives thereof and mixtures thereof, in combination with a pharmaceutically acceptable carrier for oral administration.