US 2003/0114354 A1 · Polynucleotide encoding a novel potassium channel with homology to the ether-a-go-go family, HEAG2

Abstract

The present invention provides novel polynucleotides encoding HEAG2 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HEAG2 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Claims18

Dependent claims

A computer for producing a three-dimensional representation of a molecule or molecular complex, wherein said molecule or molecular complex comprises the structural coordinates of the PAS domain of HEAG2 as provided in Table IV,

wherein said computer comprises:
(a) A machine-readable data storage medium, comprising a data storage material encoded with machine readable data, wherein the data is defined by the set of structure coordinates of the model;
(b) a working memory for storing instructions for processing said machine-readable data;
(c) a central-processing unit coupled to said working memory and to said machine-readable data storage medium for processing said machine readable data into said three-dimensional representation;
and
(d) a display coupled to said central-processing unit for displaying said three-dimensional representation.

3 more elements

Dependencies are inferred from the claim text.

Polynucleotide encoding a novel potassium channel with homology to the ether-a-go-go family, HEAG2

Life of this patent

Polynucleotide encoding a novel potassium channel with homology to the ether-a-go-go family, HEAG2

Life of this patent

Abstract

Claims18