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AssigneeArcher Daniels Midland Company
InventorsHungming J. Liaw, John Eddington, Yueqin Yang, Richard Dancey, Stacia Swisher, Weiying Mao
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The invention provides novel microorganisms, methods for the production thereof and novel processes for the production of amino acids. Mutagenesis of parental bacterial strains and selection of an improved raffinate-resistant phenotype enables the isolation of strains with enhanced growth properties that produce larger amounts of amino acid. Microorganisms of the invention are produced from amino acid producing parental strains such as Corynebacterium or Brevibacterium, particularly preferred are parental strains that produce L-lysine.
A method for the production of an improved raffinate-resistant, amino acid producing bacterial strain B comprising:
A bacterial strain B that produces an amino acid produced by a process wherein:
A Corynebacterium sp. strain producing at least about 10 g/l L-lysine in 24 hours when grown in a medium containing at least about 1% raffinate.
A Brevibacterium strain producing at least about 10 g/l L-lysine in 24 hours when grown in a medium containing at least about 1% raffinate.
An L-lysine producing bacterial strain, wherein said strain is selected from the group consisting of:
A process for the production of an amino acid comprising:
Dependencies are inferred from the claim text.