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US 2003/0113868 A1Published application
Human metabotropic glutamate receptor subtype mGluR7b
AssigneeNovartis AG
InventorsPeter Josef Flor, Rainer Kuhn, Kristin Lindauer, Irene Puttner, Thomas Knopfel
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Abstract
The invention provides purified human metabotropic glutamate receptors, compositions comprising such receptors, and nucleic acids that encode such receptors.
Claims33
Purified human metabotropic glutamate receptor (hmGluR) which is a member of the hmGluR4 subfamily selected from the group consisting of subtypes hmGluR4, hmGluR6 and hmGluR7, wherein hmGluR4 has the amino acid sequence set forth in SEQ ID NO:2;
- hmGluR7 is selected from the group consisting of hmGluR7a having the amino acid sequence set forth in SEQ ID NO:12, hmGluR7b having the amino acid sequence set forth in SEQ ID NO:14 and a hmGluR7 subtype comprising a polypeptide having an amino acid sequence set forth in SEQ ID NO:
- 6, 8 or 10, respectively;
- and hmGluR6 comprises a polypeptide having the amino acid sequence set forth in SEQ ID NO:16.
Dependencies are inferred from the claim text.