Epoxide polymer surfaces
AssigneeSurModics, Inc.
InventorsDale G. Swan, Melvin J. Swanson
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Abstract
Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes epoxide groups capable of covalently binding to the target molecule. Optionally, the composition can contain photoreactive groups for use in attaching the reagent composition to the surface. The reagent composition can be used to provide activated slides for use in preparing microarrays of nucleic acids.
Claims28
A reagent composition for attaching a target molecule to the surface of a substrate, the reagent composition comprising a polymeric backbone adapted to be covalently attached to the surface and comprising one or more pendent epoxide groups adapted to form covalent bonds with corresponding functional groups on the target molecule.
Dependencies are inferred from the claim text.