Rotavirus enterotoxin adjuvant
AssigneeBaylor College of Medicine
InventorMary K. Estes
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Abstract
This invention relates to a method of potentiating an immune response by administering a viral enterotoxin or derivative as an adjuvant. More particularly it relates to administering a viral enterotoxin or derivative as an adjuvant and an antigen to a mucosal surface of a mammal.
Claims18
A method of potentiating an immune response against an antigen in an animal comprising the step of administering to said animal said antigen and an adjuvant wherein said adjuvant is a rotavirus enterotoxin or a derivative thereof.
A method of potentiating an immune response against influenza A virus in an animal comprising the steps of administering to a mucosal surface of said animal, an inactivated influenza A virus, and administering an adjuvant wherein said adjuvant is rotavirus enterotoxin or a derivative thereof.
A method of potentiating an immune response to rotavirus-like particles in an animal comprising the steps of administering to a mucosal surface of said animal rotavirus-like particles and administering an adjuvant wherein said adjuvant is rotavirus enterotoxin or a derivative thereof.
Dependencies are inferred from the claim text.