Method for assessing the risk of cardiovascular disease
OwnerJukka Saloneninventor
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Abstract
The present invention is directed to a method identifying a condition in an individual in which elevation of serum or plasma HDL concentration or HDL cholesterol concentration provides enhanced protection against cardiovascular disease, the method comprising the step of testing the individual for a disorder that detrimentally affects the protective effect of HDL, whereby absence of such a disorder is an indication of enhanced protection against cardiovascular disease when said individual exhibits elevated serum or plasma HDL or HDL cholesterol concentration.
Claims28
A method of identifying a condition in an individual in which an elevated serum or plasma HDL concentration, or HDL cholesterol concentration, provides enhanced protection against cardiovascular disease, the method comprising the step of testing the individual for a disorder that detrimentally affects the protective effect of HDL, whereby absence of such a disorder is an indication of enhanced protection against cardiovascular disease when said individual exhibits elevated serum or plasma HDL or HDL cholesterol concentration.
The method according to any one of the preceding claims, wherein the cardiovascular disease is coronary heart disease or cerebrovascular disease.
Method of treatment of an individual in order to protect the said individual against the risk of cardiovascular disease, the method comprising the steps of testing the said individual for a disorder which detrimentally affects the protective effect of HDL, identifying and selecting an individual free of said condition, and treating the selected individual in order to enhance the HDL or HDL cholesterol level of said individual.
A kit for identifying a condition in an individual in which condition an elevated serum or plasma HDL or HDL cholesterol concentration provides enhanced protection against cardiovascular disease, or for predicting an individual's response to HDL or HDL cholesterol elevating treatments, wherein the kit comprises means for testing the individual for a disorder which detrimentally affects the protective effect of HDL
Dependencies are inferred from the claim text.