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AssigneePhoqus Pharmaceuticals Limited
InventorTrevor Ian Martin
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This invention concerns a powder material suitable for electrostatic application to a substrate and a method of electrostatically applying said powder material to a substrate. At least some of the particles which constitute the powder material comprise a core and a shell surrounding the core. The shell and core generally have differing compositions and have different chemical and/or physical properties. Components which are likely to be altered can be placed in the core whilst maintaining the shell composition, thus allowing changes in formulation of the powder material without destroying the performance of the material in electrostatic application. The powder material is especially suitable for electrostatic application to pharmaceutical solid dosage forms.
A method of electrostatically applying powder material to a substrate, wherein at least some of the particles of the material comprise a core and a shell surrounding the core, the material of the core and the shell having different physical and/or chemical properties.
A powder material suitable for electrostatic application to a substrate, wherein at least some of the particles of the material comprise a core and a shell surrounding the core, the material of the core and the shell having different physical and/or chemical properties.
A pharmaceutically acceptable powder material suitable for electrostatic application to a pharmaceutical substrate, wherein at least some of the particles of the material comprise a core and a shell surrounding the core, the material of the core and the shell having different physical and/or chemical properties.
A powder material suitable for electrostatic application to a substrate, wherein at least some of the particles of the material comprise a core and a shell surrounding the core, the material of the core and the shell having different physical and/or chemical properties, and which includes biologically active material.
A powder material suitable for electrostatic application to a substrate, wherein at least some of the particles of the material comprise a core and a shell surrounding the core, the material of the core and the shell having different physical and/or chemical properties, wherein at least one component present in the core is not present in the shell and at least one component present in the shell is not present in the core and wherein the powder material is fusible at a temperature of no more than 150° C. at atmospheric pressure to form a continuous film coating, is soluble in aqueous media and includes a charge-control agent or a polymer having charge-control functionality
A method of preparing a range of powder materials for electrostatic application to pharmaceutical substrates, the particles of each of the powder materials comprising a core and a shell surrounding the core, which method comprises, for each powder material, encapsulating the desired core material, the core material comprising a binder polymer and one or more additives selected from a colorant, an opacifier, a biologically active material and a filler and optionally one or more other additives, with a shell material having different physical and/or chemical properties from the core material and comprising a binder polymer and optionally one or more other additives, and wherein the same shell material is used for the range of powder materials produced.
Dependencies are inferred from the claim text.