Proteoglycan compositions for treating arthritic inflammatory conduitions
OwnerTheoharis C. Theoharidesinventor
Life of this patent
Estimating the term…
Abstract
Compositions with synergistic anti-inflammatory effects in inflammatory diseases resulting from activation and consequent degranulation of mast cells and followed by secretion of inflammatory biomolecules from the activated mast cells, composed of a heavily sulfated, non-bovine proteoglycan such as shark cartilage chondroitin sulfate C, and one or more of a hexosamine sulfate such as D-glucosamine sulfate, a flavone such as quercetin, an unrefined olive kernel extract that increases absorption of these compositions in various routes of administration, S-adenosylmethionine, a histamine-1 receptor antagonist, a histamine-3 receptor agonist, an antagonist of the actions of CRH, caffeine, and a polyamine.
Claims39
A composition with synergistic anti-inflammatory properties in conditions induced by the activation of mast cells, consequent degranulation of said cells and secretion of inflammatory biomolecules, comprising a non-bovine proteoglycan sulfate and one or more of a hexosamine sulfate, a flavone, an unrefined olive kernel extract, S-adenosylmethionine (“SAM”), a histamine-1 receptor antagonist, a histamine-3 agonist, an antagonist of the actions of Corticotropin Releasing Hormone (“CRH”), a hyaluronate salt, a rutin, a polyamine, and caffeine, in an appropriate excipient or vehicle.
The composition according to claim1, wherein said inflammatory disease is allergic conjunctivitis, comprising quercetin 0.05%, chondroitin sulfate 2.0%, and, optionally, azelastine 0.05%.
Dependencies are inferred from the claim text.