A method of reducing body fat in a human, which comprises the step of administering a dose, including a simmondson component as an active ingredient, selected from the group consisting of jojoba, defatted jojoba meal, jojoba extract, defatted jojoba meal extract, simmondsin, naturally derived simmondsin, synthesized simmondsin, naturally derived simmondsin derivative, synthesized simmondsin derivative, naturally derived simmondsin analogues, and synthesized simmondsin analogues or a mixture thereof, to reduce the human's body fat, wherein the dose provides the active ingredient in an amount greater than 0.01% of one's total daily diet by weight.