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US 2003/0113381 A1Published application
Chelated 8-hydroxyquinoline and use thereof in a method of treating epithelial lesions
AssigneeDermex Pharmaceuticals, LLC
InventorsRussel T. Jordan, Carl C. Hanson, Frank S. Potestio
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Abstract
A chelation complex including 8-hydroxyquinoline and zinc mixed with a carrier demonstrates therapeutic efficacy in treating lesions including cancerous lesions, precancerous lesions, cysts and warts.
Claims25
A composition for use in treating epithelial lesions comprising:
- 8-hydroxyquinoline;
- a metal chelating agent;
- and
- a carrier,
- wherein said 8-hydroxyquinoline and said metal chelating agent are present in therapeutically effective amounts providing means for selectively eliminating lesions selected from the group consisting of cancerous lesions, precancerous lesions, cysts, and warts.
2 more elements
A composition for use in treating epithelial lesions comprising:
- 8-hydroxyquinoline;
- a metal chelating agent;
- and
- a carrier,
- wherein said 8-hydroxyquinoline and said metal chelating agent are present in therapeutically effective amounts providing means for selectively eliminating lesions selected from the group consisting of acanthosis nigricans, acne, acral lick dermatitis, allergic reactions, calcinosis circumscripta, calcinosis cutis, cutaneous asthenia, deep mycotic infection, demodicosis, acute and chronic dermatitis, dermatomycosis, eosinophillic granuloma complex, epidermal cysts, hypothyroidism, ichthyosis, insect bites, lentigo, nodular penniculitis, pemphigus, canine scabies, and thallium toxicosis.
2 more elements
A composition for use in treating epithelial lesions comprising:
- 8-hydroxyquinoline;
- a metal chelating agent;
- and
- a carrier,
- wherein said 8-hydroxyquinoline and said metal chelating agent are present in therapeutically effective amounts providing means for selectively eliminating lesions selected from the group consisting of basal cell tumors, fibroma, fibrosarcoma, granuloma, hemangioma, hemangiopericytioma, histiocytoma, intracuaneous cornyfying epithelioma, lipoma, lymphosarcoma, mast cell tumor, melanoma, papilloma, periana adenoma, reticulum cell sarcvoma, sebaceouos gland tumor, squamous cell carcinoma, sweat gland (apocrine) tumor, and transmissible venereal tumor.
2 more elements
Dependencies are inferred from the claim text.