Method and pharmaceutical composition for inhibiting premature rapture of fetal membranes, ripening of uterine cervix and preterm labor in mammals
OwnerShamir Leibovitzinventor
Life of this patent
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Abstract
A method and a pharmaceutical composition for inhibiting premature rapture of the fetal membranes, ripening of the uterine cervix and preterm labor of female mammals including human. The method includes the step of administering compounds for reversing at least two biochemical conditions being associated with the above processes. The pharmaceutical composition includes compounds for reversing at least two biochemical conditions being associated with the above processes.
Claims13
A method of preventing premature ripening of the cervix and preterm labor in a pregnant female comprising the step of administering compounds formulated for reversing at least two biochemical conditions being associated with ripening of the cervix and preterm labor, said compounds comprising an inhibitor of cervical collagenase and at least one additional compound for reversing at least one biochemical condition being associated with premature ripening of the cervix and preterm labor selected from the group consisting of high level of cytokines, low ratio of high affinity receptor mediated progesterone effect versus estrogen effect, low level of nitric oxide, high level of high affinity receptor mediated prostaglandins effect and high level of high affinity receptor mediated oxytocin effect, thereby inhibiting at least one symptom of premature ripening of the cervix and/or preterm labor in the pregnant female mammal.
The method of claim 17 further comprising the step of administering a conventional treatment for preventing ripening of the cervix and preterm labor.
Dependencies are inferred from the claim text.