Differential spr sensor and measuring method using it
OwnerIsao Karube, Takuo Akimotoinventors
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OwnerIsao Karube, Takuo Akimotoinventors
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The present invention provides a differential SPR sensor that is capable of independently determining resonance wavelenghts without determining a baseline. A differential SPR sensor is formed with a surface immobilized with a recognition component and a surface not immobilized with the component on a metal film. The sensor comprises a plurality of dielectric films of different film thicknesses formed on the metal film, wherein one of said dielectric films is taken to be a reference surface and at least the other one dielectric film is taken to be a working surface immobilized with the recognition component. Preferably, the sensor is a probe-type SPR sensor, and a working surface and a reference surface are formed on a metal film providing a sensor surface of the probe.
A differential SPR sensor formed with a surface immobilized with a recognition substance and a surface not immobilized with the substance on a metal film, said sensor comprising a plurality of dielectric films of differing film thicknesses formed on the metal film, wherein one of said dielectric films is taken to be a reference surface and at least the other one dielectric film is taken to be a working surface immobilized with the recognition substance.
The method of using a differential SPR sensor, said sensor formed with a surface immobilized with a recognition substance and a surface not immobilized with the substance on a metal film, said sensors comprising a plurality of dielectric films of differing film thicknesses formed on the metal film, wherein one dielectric film is taken to be a reference surface and at least the other one dielectric film is taken to be a working surface immobilized with the recognition substance, wherein a substance to be measured is measured by comparing a result obtained from the working surface and a result obtained from the reference surface.
Dependencies are inferred from the claim text.