Method for biomolecular sensing and system thereof
AssigneeUniversity of Rochester
InventorsBenjamin Miller, Lewis Rothberg
Life of this patent
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Abstract
A sensing system and method for biomolecular sensing. The system includes: a receptor for the at least one target, the receptor including a substrate and a transparent coating on the substrate having front and back surfaces; a light source positioned to direct at least a portion of light from the light source toward the coating on the receptor; and a detector positioned to capture the light reflected from the front and back surfaces of the coating, the detector identifying presence of at least one target based on a change in the interference pattern of captured light.
Claims26
A sensor system for sensing at least one target, the system comprising:
- a receptor for the at least one target, the receptor comprising a substrate and a translucent coating on the substrate having front and back surfaces;
- a light source positioned to direct at least a portion of light from the light source toward the coating on the receptor in a manner effective to result in a condition of near perfect interference;
- and
- a detector positioned to measure the light reflected from the front and back surfaces of the coating, the detector identifying presence of at least one target based on the measured reflected light.
A method for sensing at least one target, the method comprising:
- providing a receptor for the at least one target, the receptor comprising a substrate and a translucent coating on the substrate having front and back surfaces;
- directing a light at the front and back surfaces of the coating on the receptor in a manner effective to result in a condition of near perfect interference;
- measuring the light reflected from the front and back surfaces of the coating on the receptor;
- and
- providing an output identifying the at least one target based on the measured reflected light.
Dependencies are inferred from the claim text.