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US 2003/0077802 A1Published application
Human PRL1 phosphatase
AssigneeIncyte Genomics, Inc.
InventorsJanice Au-Young, Karl J. Guegler, Neil C. Corley
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Abstract
The invention provides a human PRL-1 phosphatase (HPRL-1) and polynucleotides which identify and encode HPRL-1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HPRL-1.
Claims56
An isolated polypeptide selected from the group consisting of:
- a) a polypeptide comprising the amino acid sequence of SEQ ID NO:1,
- b) a polypeptide comprising a naturally occurring amino acid sequence at least 90% identical to the amino acid sequence of SEQ ID NO:1,
- c) a fragment of a polypeptide having the amino acid sequence of SEQ ID NO:1, said fragment having phosphatase activity, and
- d) an immunogenic fragment of a polypeptide having the amino acid sequence of SEQ ID NO:1.
1 more element
An isolated polynucleotide selected from the group consisting of:
- a) a polynucleotide comprising a polynucleotide sequence of SEQ ID NO:2,
- b) a polynucleotide comprising a naturally occurring polynucleotide sequence at least 90% identical to a polynucleotide sequence of SEQ ID NO:2,
- c) a polynucleotide complementary to a polynucleotide of a),
- d) a polynucleotide complementary to a polynucleotide of b) and
- e) an RNA equivalent of a)-d).
2 more elements
Dependencies are inferred from the claim text.