Nuclear magnetic resonance spectrometer for liquid-solution
AssigneeHitachi, Ltd.
InventorsMichiya Okada, Tsuyoshi Wakuda, Shigeru Kakugawa, Hiroshi Morita, Katsuzo Aihara
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Abstract
In a nuclear magnetic resonance spectrometer, the shape of a detection coil is changed from a conventional cage type to a solenoid type of higher sensitivity. Accordingly, differing from the conventional superconductive magnet of multilayer air core solenoids, a superconductive magnet is right and left divided to split magnets for generating 11 T, preferably, 14.1 T in the horizontal direction, and the magnetic field uniformity is set to 0.001 ppm or less and the temporal stability is set to 0.001 ppm or less.
Claims11
A nuclear magnetic resonance spectrometer for liquid-solution which comprises a superconductive magnet, a high-frequency transmission coil and a reception coil and in which a sample such as protein dissolved in a liquid-solution is charged in a sample tube of a diameter of 5 to 10 mm and is inserted substantially vertically, wherein a stationary magnetic field generated by said superconductive magnet is 11 T or more, the direction of the stationary magnetic field generated by said superconductive magnet is in the horizontal direction, a change per hour of proton nuclear magnetic resonance frequency due to a change of said stationary magnetic field is 1.0 Hz or less, the uniformity of said stationary magnetic field in a sample space is 1.0 Hz or less in terms of proton nuclear magnetic resonance frequency, said liquid-solution sample is inserted in the magnetic field center substantially vertically from above, and said reception coil is a solenoid coil inserted in the magnetic field center from below the spectrometer.
A nuclear magnetic resonance spectrometer for liquid-solution which comprises a superconductive magnet, a high-frequency transmission coil and a reception coil and in which a sample such as protein dissolved in a liquid-solution is charged in a sample tube of a diameter of 5 to 10 mm and is inserted substantially vertically, wherein a stationary magnetic field generated by said superconductive magnet is 11 T or more, the direction of the stationary magnetic field generated by said superconductive magnet is in the horizontal direction, a change per hour of proton nuclear magnetic resonance frequency due to a change of said stationary magnetic field is 1.0 Hz or less, the uniformity of said stationary magnetic field in a sample space is 1.0 Hz or less in terms of proton nuclear magnetic resonance frequency, said liquid-solution sample is inserted substantially vertically from above in the magnetic field center, and said reception coil is a solenoid coil made of a superconductive material, inserted in the magnetic field center from below the spectrometer and cooled to a superconductivity revealing temperature or less.
A nuclear magnetic resonance spectrometer for liquid-solution which comprises a superconductive magnet, a high-frequency transmission coil and a reception coil and in which a sample such as protein dissolved in a liquid-solution is charged in a sample tube of a diameter of 5 to 10 mm and is inserted substantially vertically from above, wherein a stationary magnetic field generated by said superconductive magnet is 11 T or more, said superconductive magnet is a toroidal magnet placed in the horizontal direction, a change per hour of proton nuclear magnetic resonance frequency due to a change of said stationary magnetic field is 1.0 Hz or less, the magnetic field uniformity in a sample space is 1.0 Hz or less in terms of proton nuclear magnetic resonance frequency, a plurality of liquid-solution samples are placed circumferentially of the toroidal coil at intervals of substantially equidistance, and the reception coil corresponding to each sample is a solenoid coil made of a superconductive material, inserted in the center of said magnetic field from below the spectrometer and cooled to a superconductivity revealing temperature or less.
A nuclear magnetic resonance spectrometer for liquid-solution wherein a liquid-solution sample is placed in the center of a magnetic field from below the spectrometer, a detection coil is a solenoid coil placed in the magnetic field center from below the spectrometer, and a superconductive magnet is right and left divided into split magnets.
Dependencies are inferred from the claim text.