Haemophilus adherence and penetration proteins
AssigneeWashington University
InventorJoseph W. ST. Geme III
Life of this patent
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Abstract
Haemophilus adhesion and penetration proteins, nucleic acids, vaccines and monoclonal antibodies are provided.
Claims16
A recombinant Haemophilus adhesion and penetration protein encoded by a nucleic acid selected from the group consisting of SEQ ID NO:
- 8, 10, 12, 14 and 16.
A recombinant Haemophilus adhesion and penetration protein which has a sequence selected from the group consisting of the sequence shown in SEQ ID NOS 7, 9, 11 and 13.
A recombinant nucleic acid that will hybridize under high stringency conditions to a nucleic acid selected from the group consisting of the sequence shown in SEQ ID NOS 8, 10, 12, 14 and 16.
A method of producing an Haemophilus adhesion and penetration protein comprising:
- a) culturing a host cell transformed with an expressing vector comprising a nucleic acid encoding an Haemophilus adhesion and penetration protein;
- and
- b) expressing said nucleic acid to produce an Haemophilus adhesion and penetration protein.
A composition comprising an antibody capable of binding to an Haemophilus adhesion and penetration protein.
A composition comprising a peptide selected from the group consisting of the peptides set forth in Table 1.
Dependencies are inferred from the claim text.