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AssigneeSensys Medical, Inc.
InventorsThomas B. Blank, George Acosta, Mutua Mattu, Marcy Makarewicz, Stephen L. Monfre, Alexander D. Lorenz, Timothy L. Ruchti
Estimating the term…
An optical sampling interface system minimizes and compensates error resulting from sampling variations and measurement site state fluctuations. Components include: An optical probe placement guide having an aperture wherein the optical probe is received, facilitates repeatable placement accuracy on surface of a tissue measurement site with minimal, repeatable disturbance to surface tissue. The aperture creates a tissue meniscus that minimizes interference due to surface irregularities and controls variation in tissue volume sampled; an occlusive element placed over the tissue meniscus isolates the meniscus from environmental fluctuations, stabilizing hydration at the site and thus, surface tension; an optical coupling medium eliminates air gaps between skin surface and optical probe; a bias correction element applies a bias correction to spectral measurements, and associated analyte measurements. When the guide is replaced, a new bias correction is determined for measurements done with the new placement. Separate components of system can be individually deployed.
An optical probe placement guide for repeatably coupling an optical probe to a targeted measurement site, comprising:
An optical sampling interface system comprising:
A method of compensating measurement bias in noninvasive analyte measurement, said bias resulting from variations sampled volume and measurement conditions between measurements, comprising the steps of:
An apparatus for minimizing optical sampling error at a tissue measurement site due to fluctuations of surface conditions, comprising any of:
Dependencies are inferred from the claim text.