Method and apparatus for calculating blood flow parameters
AssigneeThe John P. Robarts Research Institute
InventorTing Y. Lee
Life of this patent
Estimating the term…
Abstract
A method for determining tissue type includes quantitatively determining a tissue blood flow (TBF) by deconvoluting Q(t) and Ca(t), where Q(t) represents a curve of specific mass of contrast, and Ca(t) represents an arterial curve of contrast concentration, and quantitatively determining a tissue blood volume (TBV) by deconvoluting Q(t) and Ca(t). The method also includes quantitatively determining a tissue mean transit time (TMTT) by deconvoluting Q(t) and Ca(t), and quantitatively determining a tissue capillary permeability surface area product (TPS) by deconvoluting Q(t) and Ca(t). The method also includes determining a tissue type based on the TBF, the TBV, the TMTT, and the TPS.
Claims31
A method for determining tissue type, said method comprising:
- quantitatively determining a tissue blood flow (TBF) by deconvoluting Q(t) and Ca(t), where Q(t) represents a curve of specific mass of contrast, and Ca(t) represents an arterial curve of contrast concentration;
- quantitatively determining a tissue blood volume (TBV) by deconvoluting Q(t) and Ca(t);
- quantitatively determining a tissue mean transit time (TMTT) by deconvoluting Q(t) and Ca(t);
- quantitatively determining a tissue capillary permeability surface area product (TPS) by deconvoluting Q(t) and Ca(t);
- and
- determining a tissue type based on the TBF, the TBV, the TMTT, and the TPS.
A system comprising at least one of a computed tomography system and a nuclear magnetic resonance system, said system configured to:
- quantitatively determine a tissue blood flow (TBF) by deconvoluting Q(t) and Ca(t), where Q(t) represents a curve of specific mass of contrast, and Ca(t) represents an arterial curve of contrast concentration;
- quantitatively determine a tissue blood volume (TBV) by deconvoluting Q(t) and Ca(t);
- quantitatively determine a tissue mean transit time (TMTT) by deconvoluting Q(t) and Ca(t);
- quantitatively determine a tissue capillary permeability surface area product (TPS) by deconvoluting Q(t) and Ca(t);
- and
- determine a tissue type based on the TBF, the TBV, the TMTT, and the TPS.
A computer readable medium encoded with a program executable by a computer for processing scanning data, said program configured to instruct the computer to:
- quantitatively determine a tissue blood flow (TBF) by deconvoluting Q(t) and Ca(t), where Q(t) represents a curve of specific mass of contrast, and Ca(t) represents an arterial curve of contrast concentration;
- quantitatively determine a tissue blood volume (TBV) by deconvoluting Q(t) and Ca(t);
- quantitatively determine a tissue mean transit time (TMTT) by deconvoluting Q(t) and Ca(t);
- quantitatively determine a tissue capillary permeability surface area product (TPS) by deconvoluting Q(t) and Ca(t);
- and
- determine a tissue type based on the TBF, the TBV, the TMTT, and the TPS.
Dependencies are inferred from the claim text.