System and method for bi-chamber stimulation using dynamically adapted interpulse delay
AssigneePacesetter, Inc.
InventorMatthew G. Fishler
Life of this patent
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Abstract
An implantable stimulation device and associated method allow for the selection of an inter-ventricular or inter-atrial delay which results in optimal hemodynamic benefit for the patient. The stimulation device monitors and measures the width of the QRS complex, or a P wave in response to different interpulse delays during biventricular or biatrial stimulation. The stimulation device then selects the optimal interpulse delay that results in the minimum QRS or P width. The present method allows for the adaptive adjustment of the interpulse interval over time, caused for example, by changes in disease state, medical therapy, physical activity or other factors may cause changes in the electromechanical response of the heart.
Claims29
An optimization method for use in a multi-chamber cardiac stimulation device, comprising:
- setting a baseline interpulse delay between a stimulation of a first cardiac chamber on one side of a heart and a stimulation of a second cardiac chamber on another side of the heart;
- delivering a first stimulation to the first cardiac chamber;
- delivering a second stimulation to the second cardiac chamber after the baseline interpulse delay has transpired;
- measuring a baseline width of a depolarization event associated with the baseline interpulse delay, in response to the first and second stimulations;
- and
- iteratively determining an optimal interpulse delay that results in an optimum width of the depolarization event.
A multi-chamber cardiac stimulation device comprising:
- a sense system, coupled to a plurality of electrodes, that senses a cardiac signal in a first cardiac chamber on one side of a heart and a second cardiac chamber on another side of the heart;
- a pulse generator, connected to at least some of the plurality of electrodes, to generate stimulation energy;
- wherein at least some of the plurality of electrodes selectively deliver stimulation energy to any one or more of the first or second cardiac chambers;
- and
- a controller, connected to the pulse generator, that sets a baseline interpulse delay between the first cardiac chamber and the second cardiac chamber, that measures a baseline width of a depolarization event associated with the baseline interpulse delay, in response to the stimulation energy, and that iteratively determines an optimal interpulse delay which results in an optimum width of the depolarization event.
A bi-chamber cardiac stimulation device comprising:
- means for sensing a cardiac signal in a first cardiac chamber on one side of a heart and a second cardiac chamber on another side of the heart;
- means for generating stimulation energy;
- means for selectively delivering the stimulation energy to any one or more of the first or second cardiac chambers;
- means for setting a baseline interpulse delay between the first cardiac chamber and the second cardiac chamber;
- means for measuring a baseline width of a depolarization event associated with the baseline interpulse delay, in response to the stimulation energy;
- and
- means for iteratively determining an optimal interpulse delay that results in a minimum width of the depolarization event.
Dependencies are inferred from the claim text.