Cassettes supporting intracranial perfusions
OwnerJames C. Barnitzinventor
Life of this patent
Estimating the term…
Abstract
Devices and kits for intracranial and other perfusions and methods of using the same including a container having a top and bottom including a flexible bag adapted to be suspended in top to bottom orientation and to hold, in a main chamber, a solution, suspension or emulsion filled up to a fill line, a first opening to the bag located below the fill line and adapted to be fitted to conduit, a second opening located below the fill line and adapted to be fitted to conduit, and a first fluid pathway incorporated into the bag adapted to conduct fluid pumped into the second opening from below the fill line to an outlet within the bag located above the fill line.
Claims34
A container having a top and bottom comprising:
- a flexible bag adapted to be suspended in top to bottom orientation and to hold, in a main chamber, a solution, suspension or emulsion filled up to a fill line;
- a first opening to the bag located below the fill line and adapted to be fitted to conduit;
- a second opening located below the fill line and adapted to be fitted to conduit;
- and
- a first fluid pathway incorporated into the bag adapted to conduct fluid pumped into the second opening from below the fill line to an outlet within the bag located above the fill line.
A method of mixing or preventing stratification within a solution, suspension or emulsion, comprising:
- (a) pumping solution, suspension or emulsion into a bag with a sterile vent such that entering solution, suspension or emulsion is brought above the level of emulsion already within the sealed bag;
- and
- (b) pumping solution, suspension or emulsion out of the sealed bag from the bottom of the sealed bag.
A disposable cassette kit, adapted to operate with (i) a console comprising a conditioning peristaltic pump and a delivery peristaltic pump and (ii) a reservoir comprising a first opening and a second opening, the reservoir adapted for mounting on the console, the kit comprising:
- a resilient casing having an external facing, an internal facing adapted to rest against the console, and an interior space adapted to support and direct fluid conduits, wherein the casing is adapted for mounting on the console below the reservoir;
- one or more alignment slots or pegs that fit mating alignment slots or pegs in the console to correctly orient the casing;
- a first conduit from the first opening, extending through the interior space to exit the casing at a position adapted to be proximate to the conditioning peristaltic pump, the first conduit either adapted to connect with or connected with an intake of a conditioning unit that is a heat exchanger or a gas exchanger;
- a second conduit adapted to connect with or connected with an outlet of the conditioning unit and extending from such connection to the interior of the casing where it links to a first branch of a T-coupling;
- the T-coupling further comprising a second branch connecting to the second opening and a third branch connecting to a third conduit;
- and
- the third conduit extending from the third branch to exit the casing at a position adapted to be proximate to the delivery peristaltic pump.
A disposable cassette kit, adapted to operate with (i) a console comprising a delivery peristaltic pump and (ii) a reservoir comprising an opening, the reservoir adapted for mounting on the console, the kit comprising:
- a resilient casing having an external facing, an internal facing adapted to rest against the console, and an interior space adapted to support and direct fluid conduits, wherein the casing is adapted for mounting on the console below the reservoir;
- one or more alignment slots or pegs that fit mating alignment slots or pegs in the console to correctly orient the casing;
- a pathway of conduit from the first opening, wherein a segment of conduit of the pathway exits the casing, provides a loop of conduit external to the casing at a position adapted for insertion into the delivery peristaltic pump, reinserts into the casing, and connects to a heat exchanger integrated into the casing;
- the heat exchanger which (a) comprises a gasket for sealing a heat exchange fluid portion of the heat exchanger with a source of heat exchange fluid in the console or (b) is adapted to seat on a gasket provided by the source of heat exchange fluid;
- and
- a latch for attaching the casing to the console, the latch integrated into the heat exchanger and effective, when latched, to sealably seat the gasket.
A disposable cassette kit, adapted to operate with (i) a console comprising a delivery peristaltic pump and (ii) a reservoir comprising an opening, the reservoir adapted for mounting on the console, the kit comprising:
- a resilient casing having an external facing, an internal facing adapted to rest against the console, and an interior space adapted to support and direct fluid conduits, wherein the casing is adapted for mounting on the console below the reservoir;
- one or more alignment slots or pegs that fit mating alignment slots or pegs in the console to correctly orient the casing;
- a pathway of conduit from the first opening, wherein a segment of conduit of the pathway exits the casing, provides a loop of conduit external to the casing at a position adapted for insertion into the delivery peristaltic pump, reinserts into the casing, and connects to a heat exchanger integrated into the casing;
- the heat exchanger;
- a second pathway of conduit from the heat exchanger;
- and
- a plate, integral to the casing, of thermally conductive material in thermal connection with fluid of the second pathway, the plate adapted to compress against a temperature sensor seated on the console.
Dependencies are inferred from the claim text.