Pharmaceutical dipeptide compositions and methods of use thereof: immunostimulants
AssigneeCytran, Inc.
InventorsAndrei L. Kozhemyakin, Nickolai V. Sinackevich, Sergey V. Seryi, Alexei M. Rakhilov, Vyacheslav G. Morozov, Vladimir Khavinson, Lawrence R. Green
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Abstract
Methods of treatment of subjects for decreasing cell mediated autoimmunity or humoral autoimmunity by administering an R′-Glu-Trp-R″ pharmaceutical preparation useful in subjects having autoimmune diseases.
Claims24
A method for treating a subject in need thereof to increase one or more indicia of either cell mediated immunity, humoral immunity, or innate resistance to infection, comprising the step of administering an R′-Glu-Trp-R″ pharmaceutical preparation to the subject under conditions suitable for inducing said increase in said indicia.
9 The method of claim 8, wherein the value for the assay for the maturation or the activation state markers comprises a percentage of cells bearing a cell surface marker selected from among CD2, CD3, CD4, CD28, B220, surface Ig, Rag 1, Rag 2, and Ia/Mac-1.
Dependencies are inferred from the claim text.