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US 2002/0177161 A1Published application
Surface plasmon resonance biosensor for measurement of anti-glycolipid antibody levels in neuropathy
AssigneeThe Trustees of Columbia University in the City of New York
InventorsNorman Latov, Armin Alaedini
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Abstract
The present invention provides a method of detecting human antibodies in a sera solution. The invention also provides a method of quantitating anti-glycolipid antibody levels in solutions. The invention provides a method of diagnosing disease states, including neurological diseases, by quantitating a subject's antibody levels.
Claims26
A method of detecting antibodies in a solution comprising:
- a) contacting the solution with an antigen-coated surface of a sensor chip under conditions that permit anti-antigen antibodies to bind to the antigen coating;
- b) detecting the change in surface plasmon resonance signal of the sensor chip resulting from the anti-antigen antibodies binding to the antigen coating.
Dependencies are inferred from the claim text.