Aerosols containing annealed particulate salbutamol and tetrafluoroethane
OwnerMichael Thomas Riebe, Sarvajna Kumar Dwivedi +1inventors
InventorsMichael Thomas Riebe, Sarvajna Kumar Dwivedi, Li Li-Bovet
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Abstract
This invention relates to aerosol formulations of use for the administration of medicaments by inhalation. More particularly, the invention relates to a pharmaceutical aerosol formulation which comprises particulate salbutamol sulfate having a crystalline form in which the outer layer of the crystals is substantially non-amorphous; and 1,1,1,2-tetrafluoroethane. A method of treating respiratory disorders which comprises administration by inhalation of an effective amount of a pharmaceutical aerosol formulation as defined is also described.
Claims99
A drug product comprising:
- a container containing a pharmaceutical aerosol formulation comprising annealed particulate salbutamol sulphate and 1,1,1,2-tetrafluoroethane;
- and,
- a metering valve.
A drug product comprising:
- a container containing a pharmaceutical aerosol formulation comprising annealed particulate salbutamol sulphate and 1,1,1,2-tetrafluoroethane;
- and,
- a means for metering the aerosol formulation.
Dependencies are inferred from the claim text.