Parasiticidal pyrazoles
OwnerBernard Joseph Banksinventor
Life of this patent
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Abstract
Compounds of formula (I): 1 or pharmaceutically, veterinarily or agriculturally acceptable salts thereof, or pharmaceutically, veterinarily or agriculturally acceptable solvates of either entity, wherein R1 is 2,4,6-trisubstituted phenyl or 3,5-disubstituted pyridin-2-yl; R3 is hydrogen; C2 to C5 alkyl substituted with one or more halo and with hydroxy; C2 to C5 alkanoyl substituted with one or more halo; C2 to C6 alkenyl optionally substituted with one or more halo; halo; amino or CONH2; R5 is hydrogen, amino or halo; R2 and R4 are each independently selected from hydrogen, fluoro, chloro and bromo; R6 and R8 are hydrogen; and R7 is hydrogen or C1 to C4 alkyl optionally substituted with one or more halo; are parasiticidal agents.
Claims13
A compound of formula (I):
- 12
- or a pharmaceutically, veterinarily or agriculturally acceptable salt thereof, or a pharmaceutically, veterinarily or agriculturally acceptable solvate of either entity,
- wherein
- R1 is 2,4,6-trisubstituted phenyl wherein the 2- and 6-substituents are each independently selected from halo and the 4-substituent is selected from C1 to C4 alkyl optionally substituted with one or more halo, halo and pentafluorothio;
- or 3,5-disubstituted pyridin-2-yl wherein the 3-substituent is halo and the 5-substituent is selected from C1 to C4 alkyl optionally substituted with one or more halo, halo and pentafluorothio;
- R3 is hydrogen;
- C2 to C5 alkyl substituted with one or more halo and with hydroxy;
- C2 to C5 alkanoyl substituted with one or more halo;
- C2 to C6 alkenyl optionally substituted with one or more halo;
- halo;
- amino or CONH2;
- R5 is hydrogen, amino or halo;
- R2 and R4 are each independently selected from hydrogen, fluoro, chloro and bromo;
- R6 and R8 are hydrogen;
- and
- R7 is hydrogen or C1 to C4 alkyl optionally substituted with one or more halo.
Dependencies are inferred from the claim text.