Back to results
US 2002/0173552 A1Published application
Erodible polymers for injection
AssigneeGenentech, Inc.
InventorsJeffrey L. Cleland, Franklin Okumu
Life of this patent
Estimating the term…
Abstract
A composition for administration of a beneficial agent, contains a solvent mixture including a hydrophobic solvent and a hydrophilic solvent; a bioerodible polymer; and a beneficial agent. The polymer and the beneficial agent are dissolved. The composition has a low viscosity, allowing for easy injection through standard hypodermic needles.
Claims40
A composition for administration of a beneficial agent to an organism, comprising:
- a solvent mixture, comprising
- a hydrophobic solvent;
- and
- a hydrophilic solvent;
- a bioerodible polymer;
- and
- a beneficial agent,
- wherein the polymer and the beneficial agent are dissolved.
5 more elements
A composition for administration of a beneficial agent, comprising:
- a solvent mixture, comprising
- a hydrophobic solvent;
- and
- a hydrophilic solvent;
- a bioerodible polymer;
- and
- a beneficial agent,
- wherein the viscosity of the composition is less than 2000 centipoise.
5 more elements
A composition for administration of a beneficial agent to an organism, comprising:
- a solvent mixture, the solvent mixture comprising a hydrophobic solvent and a hydrophilic solvent;
- a bioerodible polymer dissolved in the solvent mixture;
- and
- a beneficial agent dissolved in the solvent mixture,
- wherein the viscosity of the composition is less than 2000 centipoise, at least 90 wt % of the solvent mixture is the hydrophobic solvent, the hydrophobic solvent has a solubility in water of less than 0.1 wt %, and less than 25% of the beneficial agent is released in 24 hours following administration in vivo.
2 more elements
A kit, comprising:
- a container;
- a hydrophobic solvent;
- a hydrophilic solvent;
- a bioerodible polymer;
- and
- a beneficial agent,
- wherein the a mount of said hydrophobic solvent and said hydrophilic solvent is sufficient together to dissolve all of said polymer.
4 more elements
Dependencies are inferred from the claim text.