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US 2002/0173533 A1Published application
Amorphous form of cell cycle inhibitor having improved solubility and bioavailability
AssigneeHoffmann-La Roche Inc.
InventorsAntonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
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Abstract
The present invention provides a method for preparing an amorphous, pharmaceutically active form of a compound of formula I 1 which is substantially free of crystalline compound.
Claims3
A method of making a compound of formula I
- 4
- in amorphous form substantially free of crystalline compound comprising:
- (a) dissolving a crystalline compound of formula I in a supercritical fluid;
- and
- (b) removing the supercritical fluid.
2 more elements
Dependencies are inferred from the claim text.