Pharmaceutical compositions comprising norastemizole
OwnerMartin P. Redmon, Hal T. Butler +1inventors
InventorsMartin P. Redmon, Hal T. Butler, Stephen A. Wald
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Abstract
The present invention relates to chemically stable pharmaceutical formulations of the potent antihistamine, norastemizole. The compositions can include norastemizole, or a pharmaceutically acceptable salt thereof; a diluent; a binder; a disintegrant; and a lubricant or the compositions can include particles of norastemizole, or a pharmaceutically acceptable salt thereof, coated with an inert coating and a pharmaceutically acceptable excipient. The present invention also relates to methods of treating allergic disorders.
Claims40
A solid pharmaceutical composition comprising norastemizole, or a pharmaceutically acceptable salt thereof;
- a diluent;
- a binder;
- a disintegrant;
- and a lubricant;
- wherein the diluent, binder, disintegrant, and lubricant are not the same.
A solid pharmaceutical composition comprising norastemizole, or a pharmaceutically acceptable salt thereof;
- microcrystalline cellulose;
- pregelatanized starch;
- croscarmellose sodium;
- and magnesium stearate.
A solid pharmaceutical composition comprising (i) a therapeutically effective amount of coated particles of norastemizole, or a pharmaceutically acceptable salt thereof, wherein said particles are coated with an inert coating and (ii) a pharmaceutically acceptable excipient.
A solid pharmaceutical composition comprising norastemizole, or a pharmaceutically acceptable salt thereof;
- a diluent;
- a binder;
- a disintegrant;
- and a lubricant;
- wherein the disintegrant is a super disintegrant.
Dependencies are inferred from the claim text.