Methods for increasing bulk density of chondroitin
AssigneeAmerican Home Products Corporation
InventorsNkere Kanu Ebube, William Antonio Mark
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Abstract
The present invention relates to a method of increasing the bulk density of chondroitin, such as that derived from marine life, by roller compacting the chondroitin. The roller compacted chondroitin may be incorporated into a solid dosage form. The claimed method may also be applied to chondroitin/glucosamine mixtures.
Claims63
A method of increasing the bulk density of chondroitin, said method comprising roller compacting said chondroitin at pressures of at least 500 psig.
A method of increasing the bulk density of a mixture of chondroitin and glucosamine (or salts thereof), said method comprising roller compacting said mixture at pressures of at least 500 psig.
A method of preparing a dosage form containing chondroitin, said method comprising:
- (A) roller compacting chondroitin at pressures of at least 500 psig, and
- (B) tableting said roller compacted chondroitin.
A method of preparing a dosage form of a mixture of chondroitin and glucosamine or a salt thereof, said method comprising:
- (A) roller compacting a mixture of chondroitin and glucosamine or a salt thereof at pressures of at least 500 psig., and
- (B) tableting said roller compacted mixture.
A solid dosage form comprising tableted, roller compacted chondroitin.
A solid dosage form comprising a tableted, roller compacted mixture of chondroitin and glucosamine or a salt thereof.
Dependencies are inferred from the claim text.