Jasmonate pharmaceutical composition for treatment of cancer

A method for treatment of prostate cancer, breast cancer, skin cancer, colon cancer, lung cancer, pancreatic cancer, lymphoma, leukemia, head and neck cancer, kidney cancer, ovarian cancer, bone cancer, liver cancer or thyroid cancer, in mammals, comprised of administering a pharmaceutical composition containing as the active ingredient a therapeutically effective amount of a jasmonate compound of Formula I:

• 6
• wherein:
• n is 0,1, or 2;
• R1 is OH, alkoxy, O-glucosyl, or imino,
• R2 is OH, O, alkoxy or O-glucosyl,
• R3, R4 and R5 are H, OH, alkoxy or O-glucosyl,
• and/or wherein R1 and R2, or R1 and R4 together form a lactone, and further wherein the bonds between C3:C7, C4:C5, and C9:C10 may be double or single bonds;
• or a derivative of said formula, wherein the derivative has at least one of the following:
• a lower acyl side chain at C3 (free acid or ester or conjugate), a keto or hydroxy (free hydroxy or ester) moiety at the C6 carbon, or an n-pentenyl or n-pentyl side chain at C7.