Nucleic acid molecules encoding human kinase and phosphatase homologues and uses therefor

A method for detecting the presence of a Kinase or Phosphatase nucleic acid molecule shown in SEQ ID NOs:1-14 in a sample comprising:

• a) contacting the sample with a nucleic acid probe or primer which selectively hybridizes to the nucleic acid molecule;
• and
• b) determining whether the nucleic acid probe or primer binds to a nucleic acid molecule in the sample to thereby detect the presence of a Kinase or Phosphatase nucleic acid molecule in the sample.

A method for identifying a compound which binds to a Kinase or Phosphatase encoded by the nucleotide sequence shown in SEQ ID NOs:1-14 comprising:

• a) contacting the Kinase or Phosphatase with a test compound under conditions suitable for binding;
• and
• b) detecting binding of the test compound to the Kinase or Phosphatase.

A method for modulating the activity of a Kinase or Phosphatase encoded by the nucleotide sequence shown in SEQ ID NOs:1-14 comprising contacting the Kinase or Phosphatase with a compound which binds to the Kinase or Phosphatase in a sufficient concentration to modulate the activity of the Kinase or Phosphatase.

A method for identifying a compound which modulates the activity of a Kinase or Phosphatase encoded by the nucleotide sequence shown in SEQ ID NOs:1-14 comprising:

• a) contacting a Kinase or Phosphatase with a test compound;
• and
• b) determining the effect of the test compound on the activity of the Kinase or Phosphatase to thereby identify a compound which modulates the activity of the Kinase or Phosphatase.