Multi-subtype FIV vaccines
AssigneesUniversity of Florida Research Foundation, Inc., The Regents of the University of California
InventorJanet K. Yamamoto
Life of this patent
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Abstract
The subject invention pertains to novel methods and compositions for protecting cats from infection by a broad range of FIV strains using a multi-subtype FIV vaccine. Multi-subtype FIV vaccines comprising either cell free whole virus or cell lines infected with viruses are described. Methods for vaccinating cats with the subject vaccine compositions are also described. Cats vaccinated according to the methods and compositions of the subject invention exhibit protective humoral and cellular immune responses to FIV when challenged with homologous or heterologous strains of FIV. The subject invention also pertains to novel feline cell lines that are susceptible to infection by FIV and their methods of use.
Claims17
A method for inducing a protective immune response against FIV infection in a susceptible host animal comprising administering to said host an effective amount of a vaccine composition that is capable of eliciting an immune response against a plurality of FIV subtypes.
A vaccine composition, comprising FIV immunogens, wherein said immunogens are capable of eliciting an immune response against a plurality of FIV subtypes in an FIV-susceptible animal.
A feline-derived T cell line, wherein said cell line is susceptible to infection by at least one FIV subtype, wherein said FIV subtype is selected from the group consisting of subtypes A, B, C and D.
Dependencies are inferred from the claim text.