Stabilized antithrombin iii preparation
AssigneeAventis Behring GmbH
InventorsJURGEN ROMISCH, HARALD STAUSS
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Abstract
A stabilized antithrombin III preparation is described which is protected against a loss of action during pasteurization by the addition of stabilizers which consist of one or more saccharides in a mixture with more than 0.5 mol/l of one or more amino acids from the group consisting of arginine, lysine, histidine, phenylalanine, tryptophan, tyrosine, aspartic acid and its salts or glutamic acid and its salts, it also being possible to additionally add glycine or glutamine to each of these amino acids.
Claims10
A stabilized antithrombin III preparation which is protected against a loss of action during pasteurization by the addition of stabilizers which consist of
- a) one or more saccharides or
- b) one or more saccharides in combination with one or more amino acids from the group consisting of arginine, lysine, histidine, phenylalanine, tryptophan, tyrosine, aspartic acid and its salts or glutamic acid and its salts, it also being additionally possible to add glycine and/or glutamine to these amino acids.
Dependencies are inferred from the claim text.