Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration
AssigneeValpharma S.A.
InventorRoberto Valducci
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Abstract
This invention refers to: multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional release granules, suitable for once-a-day administration also at high strengths of Lithium salts, and to the preparation process of said formulations.
Claims18
1) Multiparticulate formulation in form of microgranules or micro-tablets having dimensions ranging from 200 to 2000 micrometers, containing Lithium salts, characterized by the fact that said microgranules or micro-tablets have a modified release or that said microgranules or micro-tablets have partly a modified release and partly a conventional release, said formulation having a Lithium salt content of at least 500 mg/g and an in vitro dissolution profile that make it suitable for once-a-day administration.
Dependencies are inferred from the claim text.