Method for producing fibronectin and fibinogen composition using a polyalkylene glycol and glycine or b-alanine
AssigneeBaxter Aktiengesellschaft
InventorsThomas Seelich, Ralf Broermann
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Abstract
A method for producing protein compositions comprising fibrinogen and fibronectin is disclosed, wherein a fibrinogen and fibronectin-containing starting solution is treated with a precipitating composition which comprises two different components that modify the solubility of fibrinogen and/or fibronectin, so that in a single-step precipitation a precipitate is formed which comprises fibrinogen and fibronectin, and the precipitate formed optionally is further treated by methods known per se.
Claims34
A method for producing a pharmaceutical preparation comprising fibrinogen and firbronectin, characterized in that a fibrinogen and fibronectin-containing starting solution is treated with a precipitating composition which comprises two different components that modify the solubility of fibrinogen and/or fibronectin, so that in a single-step precipitation, a precipitate is formed which comprises fibrinogen and fibronectin.
The use of the biomatrix according to claim 30 for dressing wounds or as a tissue substitute, in particular as a skin substitute.
Dependencies are inferred from the claim text.